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> '''~- From the earliest days of its existence, the Institute has been involved in medical research. Much of this has been possible because of the concentration of specialist physical instrumentation and expertise which members of the Institute have developed and applied to the diagnosis and treatment of disease. In 1955 nuclear physicists first irradiated a patient with gamma radiation produced by the betatron and in the next 20 years about 2000 cancer patients were treated using this instrument. During this period many new instruments were developed and constructed for use in diagnosis with radioisotopes, including body scintillation counting and special instruments for liver and kidney. <
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> The research reactor TRIGA was used to produce radioisotopes such as radioactive fluorine and, later on, radioactive technetium and other artificial radioactive isotopes which allow rapid diagnosis of cancer, heart disease and other conditions. Much more recently, a method using neutrons for non-invasive treatment of malignant diseases (Boron Neutron Capture Therapy) is in the development stage. The aim of this method is the selective delivery of the isotope boron-10 into the tumour, using the "magic bullet" technique. Boron is coupled to an antibody, produced in the Institute, which is targeted specifically to the tumour cell surface. On irradiation with neutrons, an alpha particle is produced in situ, which destroys the malignant tisue. -~''' || [[Evolvement of research areas]]<
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>|| ||~-J. Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia, Telephone: +386 1 477 39 00<
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